Vaccines, Immunology and Clinical Trials

Pharmacodynamics of Antibiotics

The pharmacokinetic (movement of drugs) and pharmacodynamic (efficacy and toxicity of drugs at specific site of action) properties of the antibiotics are the key factors for successful working activity. This is the relationship between concentration of antibiotic and its ability to inhibit vital processes of microbial organisms. The pharmacodynamics of an antibiotic relates its pharmacokinetics to the time course of the antimicrobial activity at the site of the infection.