Vaccines Conferences 2019 | Paris | France | Immunology Meetings

Theme: Recent Advancements in Vaccination & Immunology Research

Vaccine Research 2019

Tentative program

Renowned Speakers

Nannapaneni Meghana
KIMS Institute of Medical Sciences and Research Centre
India

Said Moustafa M Eldeib
NMC Healthcare Group
UAE

Vandana Tiwari
Dr. Ram Manohar Lohia Institute of Medical Sciences
India

Sarabon Tahura
Dhaka Shishu(Children) Hospital
Bangladesh

Ndibalekera Sylvia
Makerere University College of Veterinary Medicine Animal Resources and Biosecurity
Uganda

Rudrabatla Raghuvamshi
Government Civil Hospital, Mancherial
India

Xuenan Xuan
Obihiro University of Agriculture and Veterinary Medicine
Japan

Sara M Atmani
Houari Boumediene University of Sciences and Technology
Algeria

Vaccine Research 2019

Vaccine research conference committee is going to welcome all the participants from all over the world to attain the Vaccine Research 2019 conference, which is going to be held in P aris, France during December 02-03, 2019. This gathering will give the whole concentration on existing and most recent developments in every aspect of vaccine and antibiotic research. In the light of this subject, this opportunity will provide a great platform for discussing among global scientists from different regions of vaccines, vaccinations, antibiotics and its applications. Therefore, these conference committee members are giving warm welcome all the prominent researchers, students and delegates to participate in this upcoming Vaccine Research conference event to witness a valuable scientific discussion and to participate in this session for contributing to the future innovations in this field.

Target Audience:

Heads, Deans and Professors & University Faculty
Scientists and Researchers
Vaccines and Immunization Associations and Organizations
Laboratory members and Students working in this field
Physicians in the field of Vaccine and Antibiotics
Cancer Specialists & Immune Therapists
Nurse Practitioners and Physician Assistants
Business Intelligence Experts of Pharmaceutical Industries
Vaccine and Antibiotic Manufacturing Companies
Vaccine and Antibiotic Developers and Investigators
Vaccination Programme Organizing Government and Non-government Organizations

Vaccines and Vaccination

Nowadays vaccination may be an important a part of public health and family. Vaccines work to prime your system against future “attacks” by a selected malady. It conjointly makes the system bear in mind these foreign agents. It helps to fight against several chronic and contagious diseases like poliomyelitis, mumps, HIV, HPV, small pox, cancer, Influenza, etc. The traditional vaccine consists of agents that resemble the disease-causing organism. When these agents enter the human body they stimulate the immune system to recognize these agents as foreign and destroy them. It also makes the immune system remember these foreign agents so that they can recognize and destroy the real live virulent germs. A vaccine can be administered into the body through injections, by mouth or by aerosol.

Diphtheria Vaccine
Plague and Tularemia
Ebola, Marburg, Lassa, and Machupo Virus
Q fever, Ricin toxin, Typhus fever
Nipah virus

Related Societies & Associations:

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USA:

Asia and Middle-East:

South African Immunology Society | Australasian Society of Clinical Immunology and Allergy | Asian Society of Pediatric Infectious Diseases | Korean Society of Infectious Diseases | Wildlife Conservation Society | Chinese Society Of Toxicology | Asia Pacific Association of Allergy | Asthma, and Clinical Immunology (APAAACI) | Asia Pacific Association of Pediatric Allergy, Respirology and Immunology (APAPARI) | Commonwealth of Independent States Society of Allergology and Immunology (CIS Society).

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Vaccines research and Clinical Trails

Vaccination is more important in our life for keeping us healthy.Recent years have witnessed both successes and failures of novel vaccine design and the strength of iterative approaches is increasingly appreciated. Vaccine development remains challenging because of the highly sophisticated evasion mechanisms of pathogens for which vaccines are not yet available.These combine the discovery of novel antigens, adjuvants, and vectors in the preclinical stage with computational analyses of clinical data to accelerate vaccine design. Each novel vaccine candidate needs to be evaluated for safety, immunogenicity, and protective efficacy in humans before it is licensed.

Current Challenges in vaccine R & DCurrent Focus on medicine analysis
Regulatory and Economic Aspects in medicine
Viral genetic science and genetics

Related Societies & Associations:

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USA:

Asia and Middle-East:

Wildlife Conservation Society | Annual Scientific Meeting of Indonesian Pediatric Society | Philippine Pediatric Society |Asian Society of Toxicology | Chinese Society of Toxicology; Federation of Immunological Societies of Asia | Japanese Society for Immunology; Immunology Society.

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Immunotherapy

Immunotherapy is a diagnostic method that involves either enhancement of the immune system or the hindering of the immune system. Immunotherapy is one of the most commonly used treatment for cancer. Immunotherapies are of two types, activation immunotherapies and suppression immune therapies. Immunotherapies have been proved to treat various kinds of tumours. Immunotherapies used in caner are mostly biological therapies, that is, they use substances made from living organisms. Checkpoint inhibitors, adoptive cell transfer, monoclonal antibodies etc are the types of immunotherapy that are used in cancer.

Cancer Immunotherapy
Oral immunotherapy
Immunomodulators
Humanisation antibody therapy

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Tuberculosis Vaccines

Tuberculosis (TB) Vaccines are inoculations expected for the neutralizing activity of tuberculosis. Around three out of each 10,000 people who get the counter acting agent experience indications, which are typically minor beside in to a great degree immuno-debilitated individuals. While BCG immunization gives really successful protection to infant youngsters and energetic kids, its ampleness in adults is variable, running from 0% to 80%. A few variables have been considered as accountable for the evolving results. Interest for TB immunotherapy movement exists because the infection has advanced toward winding up continuously sedate safe.

Antituberculous Vaccine Development
Pulmonary Vaccines
Pre-infection TB Vaccine

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Allergy and Asthma vaccines

The most common allergies like heavy fever or house-dust mite allergy are treated using allergy vaccines. Allergy Vaccines are more ejective in treating the insect stings like bee and wasp stings, which can be fatal in severe cases. The allergy vaccination is used by graduated doses begins with very small dose and it increases gradually.

Allergy Shots
Cortisone Shots
Asthma Vaccination
Chronic Sinus Infections

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Pediatric vaccines

In recent years, the widespread of infectious diseases in children has decreased by the pediatric vaccines. The common Pediatric vaccines are Small pox Vaccine, Hepatitis B vaccine, Diphtheria Tetanus and Pertussis Vaccines, Inactivated Polio Vaccine, Measles Mumps and Rubella Vaccine.

Hepatitis B vaccine
Diphtheria, tetanus, acellular pertussis vaccine
Haemophilus influenza type b vaccine (Hib)
Inactivated poliovirus vaccine
Pneumococcal vaccine 13-valent (PCV13)

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Toxoid Vaccines

Toxoid immunizations are delivered utilizing a toxic substance (harm) that has been made safe anyway that moves a safe response against the toxic substance. Depend upon the toxic substance made by particular microorganisms (e.g. tetanus or diphtheria). The toxic substance assaults circulatory framework and all things considered, accountable for the reactions of the illness. The protein-based toxic substance is rendered harmless and used as the antigen in the vaccination to bring out resistance.

Allergic reactions
Hypersensitivity
Biotherapeutics

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Vaccines for Infectious and Non-infectious Diseases

Vaccines are prepared to provide the protection against different kinds of viral diseases like hepatitis, viral cancer, MMR, poliomyelitis, influenza etc., different kinds of bacterial diseases like anthrax, diphtheria, tetanus, tuberculosis, typhoid, cholera and many more. Nowadays parasitic malarial vaccines and non-infectious disease vaccines like DNA vaccines for preventing tumor and allergy are also available. These molecular preparations play very important role to boost the immune system.

Viral vaccines
Bacterial vaccines
Parasitic vaccines
Non-infectious disease vaccines

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Pharmacodynamics of Antibiotics

The pharmacokinetic (movement of drugs) and pharmacodynamic (efficacy and toxicity of drugs at specific site of action) properties of the antibiotics are the key factors for successful working activity. This is the relationship between concentration of antibiotic and its ability to inhibit vital processes of microbial organisms. The pharmacodynamics of an antibiotic relates its pharmacokinetics to the time course of the antimicrobial activity at the site of the infection.

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RDT in Antibiotic Research

The industrial antibiotic yield has been enhanced by technological innovations and the development of strain improvement of microorganisms through random mutation and screening. The recombinant DNA technology and its application in antibiotic production by microorganisms have given yield enhancement and design of biosynthetic pathways for new antibiotic production. Genetic manipulation of biosynthetic pathways is very useful process for producing antagonistic products of complex bioactive metabolites.

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Side-effects of Antibiotics & Vaccines

Antibiotics are screened for side effects before getting the approval for clinical use. Some antibiotics have mild to severe side effects depending on the type of antibiotic used, targeted microbes and the individual patient. Vaccines have normally less harmful side effects like mild fever, headache, muscle joint pain; shivering etc. but few vaccines have rare side effects like allergy known as anaphylactic reaction.

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Nanotechnology in Antibiotics

Nowadays, drug-resistant bacteria can be killed by using antibiotic nanoparticles. Light activated nanoparticles can make existing antibiotics more effective for treatment of antibiotic resistance microbes. Metal oxide nanoparticles are now used as antibacterial agents. Nanocarriers such as liposomes, polymeric particles, virosomes, lipid nanoparticles etc. can help in improving the immunogenicity of new generation vaccines and protect the vaccines against degradation also.

Antibiotic nanoparticles
Metal oxide nanoparticles as antibacterial agents
Nanocarriers used for next generation vaccination

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Regulatory Affairs

Regulatory affairs which is also known as government affairs, is a professional aspect within regulated industries, such as medical devices, functional foods, biologics and pharmaceutical companies. Regulatory affairs (medical affairs) handling personnel generally has the duty for these areas like ensuring that the companies obey with all of the regulations and laws pertaining to their business and protecting public health by controlling the safety and efficacy of the products.

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Vaccination Advancement

Basically three types of vaccination strategies are used to give vaccines such as pulse vaccination strategy (repeatedly vaccinating over a defined age range), ring vaccination (vaccinating only those who are most likely to be infected) and cocooning (giving booster vaccines to mothers, family members to protect new-born babies becoming infected by them). Vaccine trial or clinical trials are required for the safety and efficacy of the vaccines. Four different phases of trials are present in trial methodology as phase one, phase two, phase three and phase four. Different types of viral, bacterial, parasitic and non-infectious disease vaccines are under research at present time like zika, adenovirus, hepatitis c, leprosy, chagas disease, Alzheimer’s disease and so on.

Pulse vaccination
Ring vaccination
Cocooning
Different phases of vaccine trials
Recent advancements in vaccine development
Reverse vaccinology

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Immunization Safety and Vaccination Schedule

Immunization safety is a wide subject area, ranging from vaccine manufacturing and regulation to the point of use of vaccine at immunization sessions, and includes the disposal of used equipment. So far in the modern generation, the development of vaccines against malaria, tuberculosis, and HIV has become a challenging entity. Vaccines are developed in accordance with the highest standards of safety because vaccines must be safe for use by as many people as possible. Each individual has a unique identity response to vaccines, and there is no way to absolutely guess the reaction of a specific individual to a particular vaccine. Vaccination is the most secure and best general successfulness equipment accessible for counteracting illness and death. Adequate immunizations ensure people whenever regulated before introduction.

Vaccine Schedule and Administration
Adverse vaccine incident
Vaccination to Global Health
Cost-effectiveness analyses and evaluation

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Vaccine Delivery Systems and Adjuvants

Vaccine adjuvants – is an ingredient of a vaccine that helps to create a stronger immune response in the patient’s body. In other words, adjuvants help vaccines work better. Few vaccines are made from weak or dead germs which contain natural adjuvants and help the body to produce a protective immune response. The amount of aluminium present in vaccines is low and is regulated by the U.S. Food and Drug Administration (FDA). Medicinal adjuvants are added to antibodies for a reaction in a secure framework to the target substance; nevertheless, do not offer of being influenced.

Simulating Immune Systems
Mechanism of Adjuvants
Organic Adjuvants
Immunologic Adjuvants

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Vaccines Manufacturing Technologies

Vaccination is the most important approach to counteract infectious diseases. Thus, the development of new and improved vaccines for existing, emerging, and re-emerging diseases is an area of great interest to the scientific community and the general public. The recent advancements in vaccines defend the folks from the wide range of diseases. The most ability of the vaccines is to induce the body substance protein responses and cell-mediated responses against the big selection of pathogens. To boot, the invention is accustomed to turning out the vaccines, immunogens and valuable therapeutic and diagnostic reagents. Among the tools available for disease prevention and control, vaccines rank high with respect to effectiveness and economic feasibility.

Cross-flow filtration
Increasing vaccine stability
Ultracentrifugation operations

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Plant-based vaccines

Plant-based vaccines are recombinant protein subunit vaccines. Ideally, the choice of plant species used to produce the selected antigen should allow for oral drug delivery in the form of an edible vaccine. Plant based vaccine technologies involved in the integration of the desired genes encoding the antigen protein for specific disease into the genome of plant tissues by various methods. In the field of science and technology developed new approaches such as agroinfiltration, electroporation, polyethene glycol treatment and sonication to replace the former methods.

Production of Plant based Vaccine
Biotherapeutics of Plant Vaccine
Plant based Vaccine against Virus
Molecular level of Plant based Vaccine
Direct Gene Delivery Method
Disadvantages of Plant Based Vaccines
Methods to Increase the Efficiency of Gene Delivery

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Veterinary vaccines

The major goals of veterinary vaccines are to improve the health and welfare of companion animals, increase production of livestock in a cost effective manner and prevent animal to human transmission from both domestic animals and wildlife. Oral rabies vaccines are widely used as foxes in Europe and racoons in USA. Trials are underway for the oral immunization of dogs in developing countries.

Veterinary Vaccines for Non Infections Diseases
Vector-based Veterinary Vaccines
Development of Veterinary Vaccines
Safety or Efficacy of a Veterinary Medicine
Vaccines for Livestock Diseases
Animal Health Outcomes and Advances
Case Reports in Animal Vaccination

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Maternal and Neonatal Vaccination

Vaccination plays an important role for both maternal and neonatal health conditions. It is so beneficial for women to be immunized to reduce chances of morbidity and mortality from vaccine-preventable diseases. Some vaccines should be given to mother before pregnancy, some during pregnancy and some post pregnancy. Neonatal vaccination is the lifetime opportunity to initiate the early protective response against infectious diseases like polio, smallpox etc.

Pre-pregnancy vaccination
Vaccination during pregnancy
Post-pregnancy vaccination
Neonatal vaccination

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Immuno-oncology

Cancer vaccines can treat existing cancer (therapeutic cancer vaccines) and prevent development of cancers. Some vaccines are autologous or patient specific. Many cancers are caused by oncoviruses like HPV, hepatitis B and also by oncobacteria like Helicobacter pylori. Nowadays, approved oncovaccines like oncophage, Sipuleucel-T are used in many countries for cancer immunotherapy.

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Antibiotics

Antibiotics are the most important antimicrobial agents for fighting against bacterial, fungal activities or infections. Three types of antibiotics are found as natural antibiotics which are produced by natural microorganisms via fermentation, semi-synthetic antibiotics that can be prepared by using natural fermentation process with chemical combination and synthetic antibiotics which are completely prepared in laboratory synthetically.

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Antibiotic Resistance

The resistance of bacteria or microbes to antibiotics is very common phenomenon. Though survival of microbe results from an inheritable resistance but the growth of resistance to antibiotics also occurs through horizontal gene transfer, which is more likely to occur for frequent antibiotic use. Antibacterial-resistant strains and species are called superbugs in some cases like E. coli bacteria superbug, multidrug-resistant tuberculosis.

Horizontal gene transfer for resistance to antibiotics
Antibacterial-resistant strains and species
E. coli bacteria superbug
Multidrug-resistant tuberculosis

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Antibiotics Advancement

Due to antimicrobial resistance phenomenon, some infectious microbes become untreatable. Various efforts have been made to develop the next generation antibiotics with novel action mechanisms which can combat against the multi-drug resistant strains of microbes. Recently, symbiotic bacteria are also used to produce antibiotics against MDR strains like odilorhabdins (ODLs).

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Vaccine Types

Vaccines are the most important biological preparations that can provide active acquired immunity against a particular disease. It consists of disease causing microorganism (like bacteria, viruses) or their disease causing substances. There are many kinds of vaccines like Recombinant Vaccines, Live Attenuated Vaccines, Inactivated Vaccines, Subunit Vaccines, Toxoid Vaccines, and Conjugate Vaccines etc., which can provide the immunization in different manner. Therefore, vaccination is very important process that one should take to be healthy and free from the diseases in future.

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New Trends in Vaccines Development

Vaccine development remains challenging because of the highly sophisticated evasion mechanisms of pathogens for which vaccines are not yet available. Recent years have witnessed both successes and failures of novel vaccine design and the strength of iterative approaches is increasingly appreciated. These combine the discovery of novel antigens, adjuvants, and vectors in the preclinical stage with computational analyses of clinical data to accelerate vaccine design. Reverse and structural vaccinology have revealed novel antigen candidates and molecular immunology has led to the formulation of promising adjuvants. Gene expression profiles and immune parameters in patients, vaccines, and healthy controls have formed the basis for bio-signatures that will provide guidelines for future vaccine design.

Antigen discovery
Immunological challenges
Aspects of pathology and host responses
Expanded testing and modelling of vaccine
Chloroplast-derived vaccines antigens and therapeutics

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The worldwide markets of vaccines and antibiotics are expected to grow because of factors like increasing prevalence of chronic diseases, growing healthcare expenditure, improvement in access to healthcare, high investment in research & development, enhancements of supports from government and stakeholders such as UNICEF, WHO, PAHO and others. According to the Ameri Research Inc., market of global vaccines was valued at $32 billion in 2016 and is anticipated to reach $61.6 billion by 2024. The human vaccine market in all over the world is predicted to reach more than $47.5 billion by 2022 with the varied demand for vaccines in high-income and developing countries.

According to Kalorama’s new report, the European vaccine market covers only commercialized vaccines and developmental vaccines for diseases that are already vaccine-preventable. The emerging vaccines are not covered for diseases that are not currently vaccine-preventable, such as Alzheimer’s disease, diabetes, Ebola infection, Epstein-Barr virus (EBV) infection, heart attack, Helicobacter pylori infection, Parkinson’s disease, etc.

The worldwide demand for antibiotics has increased significantly over the past two decades. The antibiotics market was valued at about $40,866 million in 2017, which is estimated to register a compound annual growth rate (CAGR) of 4.7%, over the forecast period of 2018 to 2023. There are a range of global pharmaceutical companies, as well as smaller firms which plays an important role in domestic regions in the production of generic drugs. Most of the antibiotics are low-cost and off-patent generic medicines which are easily and widely affordable, especially among the low income and lower-middle-income countries. In addition, the generic industries play a major role in the cost reduction of pharmaceutical drugs, which increase consumption and higher availability in worldwide.

Euro Vaccines 2018 Report

The 31^st Euro Global Summit and Expo on Vaccines & Vaccination hosted by Conferenceseries LLC Ltd during June 14-16, 2018 at TRYP BARCELONA AEROPUERTO, Barcelona, Spain with a theme “Roadmap on the future of Vaccines Research” and was a great success where eminent Keynote Speakers, Speakers, Delegates and Poster Presenters from various reputed companies and Universities made their resplendent presence and addressed the gathering.

Euro Vaccines 2018 witnessed an amalgamation of peerless speakers who enlightened the crowd with their knowledge and confabulated on various new-fangled topics related to the field of Vaccines and Therapeutics.

We would like to convey a great appreciation to following eminent people, honorable guests and Keynote speakers.

Gabriel Kristian Pedersen, Statens Serum Institut, Denmark

Carmen Alvarez-Dominguez, Instituto de Investigación Marqués de Valdecilla, Spain

Frederic J Deschamps, University Hospital of Reims, France

Randa S Hamadeh, Ministry of Public Health, Lebanon

Special thanks to our Honorable Moderator, Dr. Frederic J Deschamps for his remarkable contribution towards smooth functioning at Euro Vaccines 2018 Conference.

Conferenceseries LLC Ltd on behalf of the conference congratulates the Best Poster awardees for their outstanding performance and appreciates all the participants who put their efforts in presentations and sincerely wishes them success in future endeavours.

Conferenceseries LLC Ltd would like to convey a warm gratitude to Chairs and Co-chairs who contributed effervescently for the smooth functioning of the event, Frederic J Deschamps, University Hospital of Reims, France and Chit Laa Poh, Sunway University, Malaysia.

Euro Vaccines 2018 conference was a great success with the support of International multi professional steering committee and coordinated by Journal of Vaccines & Vaccination, Journal of Clinical & Cellular Immunology and Immunome Research.

Our sincere thanks to Organizing Committee Members for their gracious presence, support and assistance towards Euro Vaccines 2018 conference and with the enormous feedback from the participants and supporters of Euro Vaccines 2018, Conferenceseries LLC Ltd is glad to announce 2^nd International Conference on Vaccines Research, November 14-15, 2019, Geneva, Switzerland.

Vaccine Research 2019 organizing committee hereby reiterates that we are NOT authorized to assist with any Visa application works. You may be required to submit a Letter of Invitation, Letter of Abstract Acceptance and Registration Payment Receipt to the embassy.

Letter of Invitation: A Letter of Invitation is a proof that your paper submission and registration application are accepted by the conference committee board. It will be stated in English and may help with your visa application.

Token Amount: Token amount of USD 100 can be paid and payment receipt can be a proof for payment and may help with your VISA application.

**SHOULD YOUR APPLICATION BE DENIED, VACCINE RESEARCH 2019 ORGANIZING COMMITTEE CANNOT CHANGE THE DECISION OF THE MINISTRY OF FOREIGN AFFAIRS, NOR WILL WE ENGAGE IN DISCUSSION OR CORRESPONDENCE WITH THE MOFA OR THE EMBASSY ON BEHALF OF THE APPLICANT. THE REGISTRATION FEE WILL BE REFUNDED WHEN THE VISA APPLICATION OF INDIVIDUAL IS DENIED AND SHOULD SUBMIT VISA REJECTION PROOF**

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Conference Date	December 02-03, 2019
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Speaker Opportunity Closed	Day 1
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All accepted abstracts will be published in respective Our International Journals.

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2^nd International Conference on Vaccine Research and Immunology December 02-03, 2019 Paris, France

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